Pharmaceutics-1, |easy notes|

              POSOLOGY Posology :- (Derived from the greek word Posos-how much, and logos science) It is the branch of pharmacology dealing with doses.    (Most important for pediatric) Dose : Is the quantitative amount administered or taken by a patient for the intended medicinal effect. - The idea being to produce the optimum therapeutic effect in a particular patient with the lowest possible dose. Factors affecting drug dosage: -Age -Body Weight -Body Surface Area -Sex -Pathological State -Tolerance -Drug-Drug Interactions -Time Of administration -Route Of Administration -Pharmaceutical dosage form and drug physical. Age • Newborn infants (pediatric) are abnormally sensitive to certain drugs because of the immature state of their hepatic and renal function by which drugs are inactivated and eliminated from the body. Failure to detoxify and eliminate drugs results in their accumulation in the tissues to a toxic level. Body weight • The official usual doses for drugs are